Identification of N2-(1-carboxymethyl)guanine (CMG) as a guanine advanced glycation end product.
作者信息
al-Abed Y, Schleicher E, Voelter W, Liebich H, Papoulis A, Bucala R
机构信息
Picower Institute for Medical Research, Manhasset, NY 11030, USA.
出版信息
Bioorg Med Chem Lett. 1998 Aug 18;8(16):2109-10. doi: 10.1016/s0960-894x(98)00398-9.
PMID:9873495
Abstract
The reaction of D-glucose with 9-methylguanine produces N2-fructosyl-9-methylguanine, which undergoes oxidation to produce N2-(1-carboxymethyl)-9-methylguanine as a major adduct.
摘要
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