Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction.
作者信息
Tsai C Y, Park W K, Weitz-Schmidt G, Ernst B, Wong C H
机构信息
Department of Chemistry, Scripps Research Institute, La Jolla, CA 92037, USA.
出版信息
Bioorg Med Chem Lett. 1998 Sep 8;8(17):2333-8. doi: 10.1016/s0960-894x(98)00422-3.
PMID:9873537
Abstract
Application of the Ugi four-component condensation to rapidly synthesize a library of glycopeptide mimics of the tetrasaccharide SLe(x) as inhibitors of E- and P-selectin, and to study the effect of varied functionality in mimics on the inhibition is described.
摘要
Zotero 插件