Montana J G, Cooper N, Dyke H J, Gowers L, Gregory J P, Hellewell P G, Miotla J, Morris K, Naylor R, Tuladhar B, Warneck J B
Chiroscience Ltd, Cambridge Science Park, UK.
Bioorg Med Chem Lett. 1998 Oct 20;8(20):2925-30. doi: 10.1016/s0960-894x(98)00524-1.
Novel xanthine analogues are described which are selective PDE4 inhibitors with improved therapeutic potential over theophylline.
新型黄嘌呤类似物已被描述,它们是选择性磷酸二酯酶4(PDE4)抑制剂,与茶碱相比具有更高的治疗潜力。