Synthesis and evaluation of a novel series of phosphodiesterase IV inhibitors. A potential treatment for asthma.

作者信息

Beasley S C, Cooper N, Gowers L, Gregory J P, Haughan A F, Hellewell P G, Macari D, Miotla J, Montana J G, Morgan T, Naylor R, Runcie K A, Tuladhar B, Warneck J B

机构信息

Chiroscience Ltd, Cambridge.

出版信息

Bioorg Med Chem Lett. 1998 Oct 6;8(19):2629-34. doi: 10.1016/s0960-894x(98)00490-9.

DOI:10.1016/s0960-894x(98)00490-9

PMID:9873593

Abstract

The synthesis and pharmacological profile of a novel series of potent and selective phosphodiesterase type IV (PDE IV) inhibitors is described.

摘要

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