二酰基胺的合成及新型α-氨基酸衍生物α-氨基酰脲的制备。
Synthesis of diacylamines and the preparation of alpha-amino-acylureas, a new type of alpha-amino acid derivatives.
作者信息
Weisz I, Roboz J, Wolf I, Szabo J, Bekesi J G
机构信息
Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.
出版信息
Bioorg Med Chem Lett. 1998 Nov 17;8(22):3241-4. doi: 10.1016/s0960-894x(98)00593-9.
PMID:9873710
Abstract
Sixteen new and one known unsymmetrical open-chain diacylamines were synthesized by sodium methoxide catalyzed acylation of amides with carboxylic esters and acylamino-carboxylic esters, or acylureas with acylamino-carboxylic esters and alpha-amino acid esters.
摘要
通过甲醇钠催化酰胺与羧酸酯、酰氨基羧酸酯的酰化反应，或酰脲与酰氨基羧酸酯和α-氨基酸酯的反应，合成了16种新的和1种已知的不对称开链二酰基胺。
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