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琥珀酰胆碱诱发未被怀疑的贝氏肌营养不良患者心脏骤停——一例报告

Succinylcholine-induced cardiac arrest in unsuspected becker muscular dystrophy--a case report.

作者信息

Wu C C, Tseng C S, Shen C H, Yang T C, Chi K P, Ho W M

机构信息

Department of Anesthesiology, Veterans General Hospital-Taichung, Taiwan, R.O.C.

出版信息

Acta Anaesthesiol Sin. 1998 Sep;36(3):165-8.

PMID:9874866
Abstract

A five year-old boy undergoing elective tonsillectomy sustained cardiac arrest following the administration of a single dose of succinylcholine during induction of anesthesia. With a 10-minute cardiopulmonary resuscitation (CPR) during which intravenous calcium gluconate, epinephrine, and sodium bicarbonate were given and DC counter shock applied, we were successful to restore cardiac activity without neurological sequelae. The cause of cardiac arrest we speculated was hyperkalemia, possibly secondary to succinylcholine-induced rhabdomyolysis. It is suggested that succinylcholine should not be used in patients with known or suspected muscular dystrophy.

摘要

一名五岁男孩在接受择期扁桃体切除术时,麻醉诱导期给予单剂量琥珀酰胆碱后发生心脏骤停。在进行了10分钟的心肺复苏(CPR),期间给予静脉注射葡萄糖酸钙、肾上腺素和碳酸氢钠,并实施直流电除颤后,我们成功恢复了心脏活动,且无神经后遗症。我们推测心脏骤停的原因是高钾血症,可能继发于琥珀酰胆碱诱导的横纹肌溶解。建议已知或疑似患有肌肉萎缩症的患者不应使用琥珀酰胆碱。

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1
Succinylcholine-induced cardiac arrest in unsuspected becker muscular dystrophy--a case report.琥珀酰胆碱诱发未被怀疑的贝氏肌营养不良患者心脏骤停——一例报告
Acta Anaesthesiol Sin. 1998 Sep;36(3):165-8.
2
Succinylcholine-induced cardiac arrest in children with undiagnosed myopathy.琥珀酰胆碱诱发未确诊肌病儿童的心脏骤停。
Can J Anaesth. 1994 Jun;41(6):497-501. doi: 10.1007/BF03011544.
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Succinylcholine-induced cardiac arrest in unsuspected Duchenne muscular dystrophy.在未被怀疑的杜氏肌营养不良症患者中,琥珀酰胆碱诱发的心脏骤停。
Can Anaesth Soc J. 1984 Jul;31(4):444-6. doi: 10.1007/BF03015422.
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A cardiac arrest following the administration of succinylcholine.使用琥珀酰胆碱后发生心脏骤停。
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Hyperkalemic cardiac arrest following succinylcholine administration: The use of extracorporeal membrane oxygenation in an emergency situation.琥珀酰胆碱给药后高钾血症性心脏骤停:体外膜肺氧合在紧急情况下的应用。
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Hyperkalaemic cardiac arrest in a manifesting carrier of Duchenne muscular dystrophy following general anaesthesia.全身麻醉后,杜氏肌营养不良症显性携带者发生高钾血症性心脏骤停。
Eur J Pediatr. 2001 Sep;160(9):579-80. doi: 10.1007/s004310100812.
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[Anesthetic complications. The incidence of severe anesthetic complications in patients and families with progressive muscular dystrophy of the Duchenne and Becker types].[麻醉并发症。杜兴氏和贝克氏型进行性肌营养不良患者及其家属中严重麻醉并发症的发生率]
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Suxamethonium-induced cardiac arrest in unsuspected pseudohypertrophic muscular dystrophy. Case report.琥珀酰胆碱诱发未被怀疑的假肥大型肌营养不良患者心脏骤停。病例报告。
Br J Anaesth. 1971 Oct;43(10):984-6. doi: 10.1093/bja/43.10.984.
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[Heart arrest during general anesthesia in a child with unrecognized Duchenne's dystrophy].[一名未被识别出患有杜氏肌营养不良症的儿童在全身麻醉期间发生心脏骤停]
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Hyperkalemia and cardiac arrest following succinylcholine administration in a 16-year-old boy with acute nonlymphoblastic leukemia and sepsis.一名16岁急性非淋巴细胞白血病合并脓毒症男孩在使用琥珀酰胆碱后发生高钾血症和心脏骤停。
Pediatr Crit Care Med. 2007 Mar;8(2):183-5. doi: 10.1097/01.PCC.0000257103.96579.B2.

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