Hammerschlag M R, Alpert S, Rosner I, Thurston P, Semine D, McComb D, McCormack W M
Pediatrics. 1978 Jul;62(1):57-62.
Vaginal cultures from 100 healthy girls, 2 months to 15 years of age, were examined for the presence of normal and potentially pathogenic microorganisms. Corynebacterium vaginale, yeast species, and genital mycoplasmas were isolated from vaginal cultures from 13.5 %, 28%, and 28% of the girls examined, respectively. Colonization with these organisms was not associated with signs or symptoms of vaginitis. Neisseria gonorrhoeae was isolated from a 4-year-old with purulent vaginitis. Trichomonas vaginalis was recovered from two 13-year-olds, both of whom had an abnormal vaginal discharge. Vaginal antibody to Chlamydia trachomatis was found in two girls 4 and 13 years of age. In neither girl was the organism recovered from the vaginal culture. Chlamydia trachomatis was recovered from the vaginal culture of another 4-year-old who had no abnormal findings on examination. Cultures from 59 of the girls were examined for aerobic and facultatively anaerobic bacteria. Diphtheroids and Staphylococcus epidermidis were the most frequently isolated organisms. Lactobacilli were isolated most frequently from the older girls, whereas enteric organisms were isolated most frequently from the younger girls.
对100名年龄在2个月至15岁的健康女孩的阴道培养物进行检查，以确定是否存在正常和潜在致病微生物。分别从13.5%、28%和28%接受检查的女孩的阴道培养物中分离出阴道棒状杆菌、酵母菌和生殖支原体。这些微生物的定植与阴道炎的体征或症状无关。从一名患有脓性阴道炎的4岁女童中分离出淋病奈瑟菌。从两名13岁女童中检出阴道毛滴虫，她们均有异常阴道分泌物。在两名4岁和13岁的女童中发现了沙眼衣原体的阴道抗体。两名女童的阴道培养物中均未检出该病原体。从另一名4岁女童的阴道培养物中检出沙眼衣原体，该女童检查时无异常发现。对59名女孩的培养物进行需氧和兼性厌氧菌检查。类白喉杆菌和表皮葡萄球菌是最常分离出的微生物。乳酸杆菌最常从年龄较大的女孩中分离出来，而肠道微生物最常从年龄较小的女孩中分离出来。
