Hari C K, Raza S A, Clayton M I
Department of Otolaryngology and Head and Neck Surgery, Royal Gwent Hospital, Newport, U.K.
J Laryngol Otol. 1998 Sep;112(9):875-7. doi: 10.1017/s0022215100141945.
Systemic lupus erythematosus (SLE) is a multi-system autoimmune disorder that can affect the upper airway. Hydralazine has been known to cause a lupus-like syndrome that can produce the clinical manifestations of SLE. We discuss a case of hydralazine-induced lupus, presenting with acute laryngeal oedema and right vocal fold paralysis. Cessation of hydralazine therapy resulted in reversal of paralysis.