Moreira-Silva S F, Leão M E, Mendonça H F, Pereira F E
Hospital Infantil N.S. da Glória, Vitória, ES, Brasil.
Rev Inst Med Trop Sao Paulo. 1998 Jul-Aug;40(4):259-61. doi: 10.1590/s0036-46651998000400010.
In the streets of Vitória, in the State of Espírito Santo, Brazil, are large number of stray dogs, many of which are infected with Toxocara canis, suggesting a high risk for human infection. In order to investigate the prevalence of Toxocara infection in children in Espírito Santo we studied the prevalence of anti-Toxocara antibodies in 100 random inpatients over one year of age, at the Children's Hospital N.S. da Glória, the reference children's hospital for the State. All the sera were collected during the period between October 1996 and January 1997. The mean age was 6.6 +/- 4.1 yrs. (1 to 14 yrs., median 6 yrs.) and there were patients from all of the different wards of the hospital. Sixty-eight patients came from the metropolitan area of Vitória and the other 32 from 17 other municipalities. The anti-Toxocara antibodies were investigated by ELISA-IgG using a secretory-excretory antigen obtained from second stage larvae. All sera were adsorbed with Ascaris suum antigen before the test. Thirty-nine sera (39%) were positive, predominantly from boys, but the gender difference was not statistically significant (boys: 25/56 or 44.6%; girls: 14/44 or 31.8%; p = 0.311). The prevalence of positive sera was higher, but not statistically significant, in children from the urban periphery of metropolitan Vitória (formed by the cities of Vitória, Cariacica, Vila Velha, Serra and Viana) than in children from 17 other municipalities (44.1% and 28.1% respectively, p = 0.190). Although the samples studied do not represent all children living in the State of Espírito Santo, since the Children's Hospital N.S. da Glória admits only patients from the state health system, it is probable that these results indicate a high frequency of Toxocara infection in children living in Espírito Santo. Further studies of population samples are necessary to ascertain the prevalence of Toxocara infection in our country.
在巴西圣埃斯皮里图州维多利亚市的街道上，有大量流浪狗，其中许多感染了犬弓首蛔虫，这表明人类感染风险很高。为了调查圣埃斯皮里图州儿童的弓首蛔虫感染率，我们研究了在该州儿童专科医院圣格洛里亚圣母儿童医院100名一岁以上随机住院儿童中抗弓首蛔虫抗体的流行情况。所有血清均在1996年10月至1997年1月期间采集。平均年龄为6.6±4.1岁（1至14岁，中位数6岁），患者来自医院的所有不同病房。68名患者来自维多利亚市大都市区，另外32名来自其他17个城市。使用从第二期幼虫获得的分泌-排泄抗原，通过ELISA-IgG检测抗弓首蛔虫抗体。所有血清在检测前均用猪蛔虫抗原吸附。39份血清（39%）呈阳性，主要来自男孩，但性别差异无统计学意义（男孩：25/56或44.6%；女孩：14/44或31.8%；p=0.311）。来自维多利亚市大都市区城市边缘地区（由维多利亚、卡里亚西卡、维拉韦尔哈、塞拉和维亚纳市组成）的儿童中阳性血清的流行率高于来自其他17个城市的儿童，但无统计学意义（分别为44.1%和28.1%，p=0.190）。尽管所研究的样本并不代表圣埃斯皮里图州所有儿童，因为圣格洛里亚圣母儿童医院仅收治来自州卫生系统的患者，但这些结果很可能表明圣埃斯皮里图州儿童弓首蛔虫感染率很高。有必要对人群样本进行进一步研究，以确定我国弓首蛔虫感染的流行情况。
