经去污剂处理的平滑肌的收缩。
Contraction of detergent-treated smooth muscle.
作者信息
Gordon A R
出版信息
Proc Natl Acad Sci U S A. 1978 Jul;75(7):3527-30. doi: 10.1073/pnas.75.7.3527.
Abstract
After exposure of segments of rabbit taenia coli to the nonionic detergent Triton X-100, tension could be induced by increasing the [Ca2+] in the micromolar range. In the presence of a saturating [Ca2+], this preparation developed nearly 100% of the control tetanus tension recorded from the intact muscle prior to the detergent treatment. In addition, tension could be induced by increasing the [Mg2+], in the virtual absence of Ca2+. Mg2+ seems to inhibit the Ca2+-induced tension in a predominantly competitive manner.
摘要
将兔结肠带的片段暴露于非离子去污剂Triton X-100后，通过在微摩尔范围内增加[Ca2+]可诱导张力。在存在饱和[Ca2+]的情况下，该制剂产生的张力接近去污剂处理前完整肌肉记录的对照破伤风张力的100%。此外，在几乎不存在Ca2+的情况下，通过增加[Mg2+]也可诱导张力。Mg2+似乎主要以竞争性方式抑制Ca2+诱导的张力。
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