Harmelin E S, Holcombe R N, Goggin J P, Carbonell J, Wellens T
South Miami Hospital Podiatric Residency Program, Fl, USA.
J Foot Ankle Surg. 1998 Nov-Dec;37(6):540-5. doi: 10.1016/s1067-2516(98)80033-1.
Acral lentiginous melanoma is a very aggressive, malignant cutaneous tumor which has a predilection for the plantar surface of the feet, palms of the hand, and the digits. The lesion presents as a rapidly spreading, darkly pigmented patch and may display varying degrees of pigmentation. These lesions have a propensity to metastasize to the central nervous system, liver, lungs, bone, and lymph nodes. Due to the aggressive nature of these lesions, early recognition and treatment, consisting of excision in toto with clean margins, are imperative. The authors present a thorough review of the literature and an illustrative case of acral lentiginous melanoma of the lower extremity.
肢端雀斑样痣黑色素瘤是一种极具侵袭性的恶性皮肤肿瘤，好发于足底、手掌和手指。病变表现为迅速扩散的深色色素沉着斑，可能呈现不同程度的色素沉着。这些病变易于转移至中枢神经系统、肝脏、肺、骨和淋巴结。由于这些病变具有侵袭性，早期识别并进行包括完整切除且切缘干净的治疗至关重要。作者对文献进行了全面回顾，并给出了一例下肢肢端雀斑样痣黑色素瘤的病例说明。
