Sajjadi H, Paparella M M, Williams T
Minnesota Ear, Head & Neck Clinic, Minneapolis 55454, USA.
Ear Nose Throat J. 1998 Dec;77(12):975-82.
Ménière's disease is a pathologic condition of the inner ear that is characterized by vertigo, tinnitus and a progressive loss of hearing. When Ménière's disease is unresponsive to medical treatment and when destructive surgery is not advisable, patients, particularly the elderly, often benefit from endolymphatic sac enhancement, a conservative, nondestructive surgical procedure. We evaluated the outcomes of 62 such patients, aged 65 years and older, who underwent a total of 78 endolymphatic sac enhancements. We assessed their response to surgery by means of a questionnaire, which classified pre- and post-surgical data according to criteria established by the American Academy of Otolaryngology-Head and Neck Surgery. Of the 27 patients who returned questionnaires, 23 reported significant alleviation of vertigo symptoms and 19 said their hearing ability had either improved or was maintained at presurgical levels. Endolymphatic sac enhancement resulted in no mortality, and morbidity was documented in only one patient. We conclude that endolymphatic sac enhancement is a safe and viable treatment for elderly patients with Ménière's disease that is refractory to medical therapy.
梅尼埃病是一种内耳的病理状况，其特征为眩晕、耳鸣和听力渐进性丧失。当梅尼埃病对药物治疗无反应且不宜进行破坏性手术时，患者，尤其是老年患者，通常可从内淋巴囊增强术（一种保守的、非破坏性的外科手术）中获益。我们评估了62例65岁及以上接受了总共78次内淋巴囊增强术的此类患者的治疗结果。我们通过一份问卷评估他们对手术的反应，该问卷根据美国耳鼻咽喉-头颈外科学会制定的标准对手术前后的数据进行分类。在27例返回问卷的患者中，23例报告眩晕症状明显缓解，19例表示他们的听力能力有所改善或维持在术前水平。内淋巴囊增强术未导致死亡，仅1例患者有并发症记录。我们得出结论，内淋巴囊增强术对于药物治疗无效的老年梅尼埃病患者是一种安全可行的治疗方法。
