给予 D-6-甲基-8-[β-异丙基氨基乙基]麦角灵-I 后泌乳大鼠腺垂体催乳素浓度变化及腺垂体的形态学表现
Changes in the concentration of adenohypophyseal prolactin and morphological manifestations in the adenohypophysis of lactating rats after administration of D-6-methyl-8-[beta-isopropylaminoethyl] ergoline-I.
作者信息
Krejcí P, Marhan O, Ausková M, Rezábek K, Semonský M
出版信息
Experientia. 1976 Oct 15;32(10):1308-9. doi: 10.1007/BF01953109.
PMID:987925
Abstract
The four days administration of D-6-methyl-8-[beta-isopropylaminoethyl]ergoline-I (VUFB-10726) to nursing rats decreases adenohypophyseal prolactin as determined with disc electrophoresis, and produces changes in the histological appearance of adenohypophyses, which indicate the inhibition of prolaction production and secretion.
摘要
对哺乳期大鼠连续四天给予D - 6 - 甲基 - 8 - [β - 异丙基氨基乙基]麦角灵 - I（VUFB - 10726），通过圆盘电泳测定发现腺垂体催乳素减少，并使腺垂体的组织学外观发生变化，这表明催乳素的产生和分泌受到抑制。
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