Casper U, Seiffert K, Dippel E, Zouboulis C C
Universitäts-Hautklinik und Poliklinik, Klinikum Benjamin Franklin der Freien Universität Berlin.
Hautarzt. 1998 Nov;49(11):850-4. doi: 10.1007/s001050050837.
Lesions of the oral mucosa are frequently described in association with psoriasis, particularly in the pustular type. Controversy surrounds the question whether mucosal lesions can be considered as oral manifestation of psoriasis. Two patients presented with concurrent pustular psoriasis and mucosal lesions with the characteristic picture of geographic tongue. Histopathology of the mucosa showed typical features of psoriasis such as marked acanthosis, clubbing of the rete ridges, focal parakeratosis and neutrophilic infiltrates. There was parallel improvement of the skin and the mucosal lesions with systemic retinoid treatment. On the basis of the histopathological features and the clinical course we favour the hypothesis that geographic tongue is an oral manifestation of pustular psoriasis.
口腔黏膜病变常与银屑病相关,尤其是脓疱型银屑病。黏膜病变是否可被视为银屑病的口腔表现这一问题存在争议。两名患者同时患有脓疱型银屑病和具有地图舌特征性表现的黏膜病变。黏膜组织病理学显示出银屑病的典型特征,如显著的棘层肥厚、 rete嵴杵状变、局灶性角化不全和中性粒细胞浸润。全身使用维甲酸治疗后,皮肤和黏膜病变均有好转。基于组织病理学特征和临床病程,我们支持地图舌是脓疱型银屑病的口腔表现这一假说。