Verrotti A, Basciani F, Domizio S, Sabatino G, Morgese G, Chiarelli F
Department of Pediatrics, University of Chieti, Italy.
Pediatr Neurol. 1998 Nov;19(5):364-7. doi: 10.1016/s0887-8994(98)00084-8.
The concentration levels of serum lipids and lipoproteins were measured in three groups of children and adolescents treated with antiepileptic drugs: carbamazepine (14 patients), phenobarbital (20 patients), and valproic acid (20 patients). Patients treated with these drugs revealed significant changes in lipids and lipoproteins, but when the authors reevaluated the three groups of children 1 year after the end of treatment, a complete return to normal of all parameters was observed. These data demonstrate that the changes induced by these drugs are transient and reversible.
卡马西平组（14例患者）、苯巴比妥组（20例患者）和丙戊酸组（20例患者）。接受这些药物治疗的患者脂质和脂蛋白出现了显著变化，但当作者在治疗结束1年后对这三组儿童进行重新评估时，所有参数均完全恢复正常。这些数据表明，这些药物引起的变化是短暂且可逆的。
