MMWR Morb Mortal Wkly Rep. 1998 Dec 25;47(50):1091-3.
Haff disease is a syndrome of unexplained rhabdomyolysis following consumption of certain types of fish; it is caused by an unidentified toxin. Rhabdomyolysis is a clinical syndrome caused by injury to skeletal muscle that results in release of muscle cell contents into the circulation. In 1997, six cases of Haff disease were identified in the United States (four in California and two in Missouri) among persons who ate buffalo fish (Ictiobus cyprinellus), a bottom-feeding species found mostly in the Mississippi River or its tributaries. This report summarizes the investigation of these cases.
哈夫病是一种在食用某些种类的鱼类后出现不明原因横纹肌溶解的综合征；它由一种不明毒素引起。横纹肌溶解是一种由骨骼肌损伤导致肌肉细胞内容物释放到循环系统中引起的临床综合征。1997年，在美国（加利福尼亚州4例，密苏里州2例）食用牛胭脂鱼（Ictiobus cyprinellus）的人群中发现了6例哈夫病病例，牛胭脂鱼是一种主要生活在密西西比河或其支流中的底栖鱼类。本报告总结了对这些病例的调查情况。
