Aoyagi N, Sasaki A, Ishii T, Tsuchida T, Hayakawa I
No Shinkei Geka. 1976 Sep;4(9):843-52.
Experience with Radio Isotope Myelography is reported here. 169Yb-DTPA as a tracer was intrathecally injected at lumbar region in twenty three patients with various spinal cord lesions. The first scanning is perfomed after comfirming by gamma-camera that the tracer reaches to the lesion, the second and the third scannings are done according to the ascending rate of the tracer. (I) Normal scintimyelogram (A) In normal case, the shape of the Radio Isotope Myelogram well corresponds the shape of anatomical subarachnoid space. (B) In normal adult cases, the tracer comes up to the cisterna magna in 20-25 minutes after the lumbar injection. Therefore, the scintimyelographic diagnosis should be made not only by the shape but also by the ascending rapidity of the tracer. (II) Abnormal scintimyelogram Abnormal scintimyelograms could be summarized as following three categories. (A) "Delay": It means delay of the ascending of the tracer. Besides, "Transient delay" found in a case of Arnord-Chiari's malformation was proposed. (B) "Partial block": It meas a defect at the level of the lesion. This "Partial block" were observed in cases of spinal cord angioma, cervical spondylosis and spinal cord tumor etc. (C) "Complete block": It means the stagnation of the tracer below the lesion. To sum up, Rario Isotope Myelography, especially in partial block, can more easily and more sensitively represent the maximum extent of the spinal cord lesion than other myelographic study or angiographic one. On the other hand, we can not qualitatively diagnose about the lesions by its indistinct border.
本文报告了放射性同位素脊髓造影的经验。对23例患有各种脊髓病变的患者,在腰椎区域鞘内注射169镱-二乙三胺五乙酸作为示踪剂。在γ相机确认示踪剂到达病变部位后进行第一次扫描,第二次和第三次扫描根据示踪剂的上升速度进行。(I)正常脊髓闪烁造影(A)在正常情况下,放射性同位素脊髓造影的形态与解剖学蛛网膜下腔的形态非常吻合。(B)在正常成人病例中,示踪剂在腰椎注射后20 - 25分钟到达枕大池。因此,脊髓闪烁造影诊断不仅应根据示踪剂的形态,还应根据其上升速度。(II)异常脊髓闪烁造影异常脊髓闪烁造影可归纳为以下三类。(A)“延迟”:指示踪剂上升延迟。此外,还提出了在阿诺德-奇亚里畸形病例中发现的“短暂延迟”。(B)“部分梗阻”:指病变水平处的缺损。在脊髓血管瘤、颈椎病和脊髓肿瘤等病例中观察到这种“部分梗阻”。(C)“完全梗阻”:指示踪剂在病变下方停滞。总之,放射性同位素脊髓造影,尤其是在部分梗阻的情况下,比其他脊髓造影或血管造影研究更容易、更敏感地显示脊髓病变的最大范围。另一方面,由于其边界不清晰,我们无法对病变进行定性诊断。