Hong S R, Chun Y K, Kim Y J, Lim K T, Kim H S
Department of Pathology, Samsung Cheil Hospital & Women's Healthcare Center, Sungkyunkwan University, Seoul, Korea.
J Korean Med Sci. 1998 Dec;13(6):680-4. doi: 10.3346/jkms.1998.13.6.680.
The occurrence of malignant mural nodule in benign cystic common epithelial tumor of the ovary have been reported in only three cases; the case one was mucinous cystadenoma with a mural nodule of fibrosarcoma and the others were of carcinomas. Our case was another rare case of ovarian mucinous cystadenoma with mural nodule of anaplastic carcinoma in a 42-year-old woman. The cystadenoma had an unilocular cystic cavity and a mural nodule with thick multinodular solid wall. The internal cystic wall was lined with mucinous cystadenoma without any malignant features. The mural nodule showed anaplastic carcinomatous differentiation and its nature was confirmed by immunohistochemistry and electron microscopy. This tumor had metastasized to the right salpinx, uterus, cul-de-sac, periureter and mesentery.
卵巢良性囊性常见上皮性肿瘤中出现恶性壁结节的情况仅报道过3例;病例1为伴有纤维肉瘤壁结节的黏液性囊腺瘤,其他病例为癌。我们的病例是一名42岁女性,患有卵巢黏液性囊腺瘤伴间变性癌壁结节,这是另一例罕见病例。该囊腺瘤有一个单房性囊腔和一个壁结节,壁结节有厚的多结节实性壁。囊腔内壁衬以无任何恶性特征的黏液性囊腺瘤。壁结节表现为间变性癌分化,其性质经免疫组化和电子显微镜检查得以证实。该肿瘤已转移至右侧输卵管、子宫、直肠陷凹、输尿管周围和肠系膜。