Department of Obstetrics and Gynecology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Department of Obstetrics and Gynecology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Taiwan J Obstet Gynecol. 2021 Jan;60(1):136-138. doi: 10.1016/j.tjog.2020.10.002.
Osteosarcoma as a mural nodule in the ovary is extremely rare. We aimed to describe a case of a mural nodule with features of an osteosarcoma arising in an ovarian mucinous cystadenoma.
The 65-year-old woman presented with progressive abdominal swelling and poor intake. Image studies showed a huge (diameter, >30 cm) intra-abdominal multiloculated cystic lesion, suspected to be an ovarian tumor. She underwent unilateral salpingo-oophorectomy with no postoperative adjuvant therapy. She was disease-free at 16-month follow-up.
Osteosarcoma presenting as a primary ovarian neoplasm is rare, either as a pure osteosarcoma or arising from a teratoma. However, two osteosarcoma cases occurring arising from a mural nodule in an ovarian mucinous neoplasm have been reported. There is no consensus regarding the treatment strategy for osteosarcomatous mural nodules in mucinous tumors because of its rarity. More case studies are needed before its pathogenesis can be fully understood.
卵巢壁结节状骨肉瘤极为罕见。我们旨在描述一例发生在卵巢黏液性囊腺瘤中的具有骨肉瘤特征的壁结节。
这名 65 岁女性因进行性腹胀和摄入不良而就诊。影像学研究显示一个巨大的（直径>30cm）腹腔多房囊性病变，疑似卵巢肿瘤。她接受了单侧附件切除术，术后未行辅助治疗。16 个月随访时无疾病。
以原发性卵巢肿瘤形式出现的骨肉瘤罕见，无论是纯骨肉瘤还是源自畸胎瘤。然而，已有两例发生在卵巢黏液性肿瘤中的壁结节状骨肉瘤的报道。由于其罕见性，对于黏液性肿瘤中骨肉瘤性壁结节的治疗策略尚无共识。在充分了解其发病机制之前，还需要更多的病例研究。
