Whitcombe D, Newton C R, Little S
Zeneca Diagnostics Gadbrook Park Northwich Cheshire CW9 7RA UK.
Curr Opin Biotechnol. 1998 Dec;9(6):602-8. doi: 10.1016/s0958-1669(98)80137-7.
The most tangible advances in DNA diagnostics during the past year have been in enhancing existing techniques to simplify their use and improve throughput. This has led to simplified genotyping methods using homogeneous analysis coupled with spectral data output. Miniaturisation and increased throughput have also been achieved through improvements in DNA chip technology.
过去一年里,DNA诊断领域最切实的进展在于改进现有技术,以简化其使用方法并提高通量。这催生了采用均相分析结合光谱数据输出的简化基因分型方法。通过改进DNA芯片技术,还实现了小型化和通量增加。