碳水化合物磺基转移酶：细胞外通讯的介质
Carbohydrate sulfotransferases: mediators of extracellular communication.
作者信息
Bowman K G, Bertozzi C R
机构信息
Department of Chemistry, University of California, Berkeley 94720, USA.
出版信息
Chem Biol. 1999 Jan;6(1):R9-R22. doi: 10.1016/S1074-5521(99)80014-3.
PMID:9889154
Abstract
Sulfated carbohydrates mediate diverse extracellular recognition events in both normal and pathological processes. The sulfotransferases that generate specific carbohydrate 'sulfoforms' have recently been recognized as key modulators of these processes and therefore represent potential therapeutic targets.
摘要
硫酸化碳水化合物在正常和病理过程中介导多种细胞外识别事件。产生特定碳水化合物“硫酸化形式”的硫酸转移酶最近被认为是这些过程的关键调节因子，因此是潜在的治疗靶点。
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