Gaughwin M, Solomon P, Ali R
Drug and Alcohol Resource Unit, Royal Adelaide Hospital, South Australia.
Aust N Z J Public Health. 1998 Dec;22(7):771-6. doi: 10.1111/j.1467-842x.1998.tb01491.x.
To investigate correlates of retention on the South Australian Methadone Program during 1981-91.
Retrospective study of a nonstratified random sample of 229 HIV-negative clients who received methadone between January 1981 and June 1991. Data were collected from clinical records of the 229 HIV-negative clients and also from the 40 clients known to be infected with HIV during the decade.
Being HIV positive, receiving larger maximum doses of methadone, receiving methadone from a private pharmacy and enrolling later in the decade were all associated with longer retention times on the program.
This study supports the findings of previous studies, that maximum dose of methadone is crucial to retention in methadone programs, But even allowing for maximum dose, obtaining methadone from a private pharmacy was also strongly associated with retention on the program. The more 'humane' clinic policy later in the decade is likely to have increased retention and reduced illicit drug use also.
调查1981年至1991年间南澳大利亚美沙酮项目中留存率的相关因素。
对1981年1月至1991年6月期间接受美沙酮治疗的229名HIV阴性患者的非分层随机样本进行回顾性研究。数据收集自这229名HIV阴性患者的临床记录,以及该十年间已知感染HIV的40名患者的记录。
HIV呈阳性、接受更大最大剂量的美沙酮、从私人药房获取美沙酮以及在该十年后期入组均与在项目中的留存时间更长有关。
本研究支持先前研究的结果,即美沙酮的最大剂量对美沙酮项目中的留存率至关重要,但即使考虑到最大剂量,从私人药房获取美沙酮也与在项目中的留存率密切相关。该十年后期更“人性化”的诊所政策可能提高了留存率并减少了非法药物使用。