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肥大细胞与翼状胬肉

Mast cells and pterygium.

作者信息

Ratnakar K S, Goswamy V, Agarwal L P

出版信息

Acta Ophthalmol (Copenh). 1976 Jul;54(3):363-8. doi: 10.1111/j.1755-3768.1976.tb01265.x.

DOI:10.1111/j.1755-3768.1976.tb01265.x
PMID:988951
Abstract

A total of thirty pterygia were studied for mast cells using metachromatic dye (toluidine blue) together with routine histological stains. On microscopic examination, the lesion was differentiated and classified into angiomatous, fibrous and mixed varieties based on the vascular and collagenous components. The mast cell counts were undertaken in all types and were found to have significant correlation with the morphological types when compared to normal conjunctiva. 15.1 +/- 3.1, 22.7 +/- 3.8, 9.5 +/- 3.2 mast cell per mm2 were found in the angiomatous, mixed and fibrous types respectively. In the control material, the mast cell count was 12.4 +/- 2.3 per mm2. The results are discussed. It is believed that mast cells are actively involved in the genesis and progress of pterygium.

摘要

使用异染性染料(甲苯胺蓝)以及常规组织学染色法,对总共30例翼状胬肉进行了肥大细胞研究。经显微镜检查,根据血管和胶原成分,将病变区分为血管瘤样、纤维样和混合型。对所有类型均进行了肥大细胞计数,结果发现与正常结膜相比,肥大细胞计数与形态学类型存在显著相关性。血管瘤样、混合型和纤维样类型中每平方毫米分别发现有15.1±3.1、22.7±3.8和9.5±3.2个肥大细胞。在对照材料中,肥大细胞计数为每平方毫米12.4±2.3个。对结果进行了讨论。据信肥大细胞积极参与了翼状胬肉的发生和发展。

相似文献

1
Mast cells and pterygium.肥大细胞与翼状胬肉
Acta Ophthalmol (Copenh). 1976 Jul;54(3):363-8. doi: 10.1111/j.1755-3768.1976.tb01265.x.
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Mast cells in pterygium: number and phenotype.翼状胬肉中的肥大细胞:数量与表型
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The expression of vascular endothelial growth factor in mast cells promotes the neovascularisation of human pterygia.肥大细胞中血管内皮生长因子的表达促进了人翼状胬肉的血管新生。
Br J Ophthalmol. 2012 Sep;96(9):1246-51. doi: 10.1136/bjophthalmol-2012-301540. Epub 2012 Jul 11.
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Increased numbers of mast cells in pterygia.翼状胬肉中肥大细胞数量增加。
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[Pterygium and mast cells--mast cell number, phenotype, and localization of stem cell factor].
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[Pterygium and mast cells--expression of basic fibroblast growth factor increase in mast cells of the pterygium].[翼状胬肉与肥大细胞——翼状胬肉肥大细胞中碱性成纤维细胞生长因子表达增加]
Nippon Ganka Gakkai Zasshi. 1998 May;102(5):300-6.
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The mastocyte reaction in pterygium.翼状胬肉中的肥大细胞反应。
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Concomitant examination of inflammation and angiogenesis in the pathogenesis of primary moderate pterygium in a well-designed case-control study.在一项精心设计的病例对照研究中,对原发性中度翼状胬肉发病机制中的炎症和血管生成进行同步检查。
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Neovascularization and mast cells with tryptase activity increase simultaneously in human pterygium.在人类翼状胬肉中,新生血管形成和具有类胰蛋白酶活性的肥大细胞同时增加。
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Ocular mast cells. Characterization in normal and disease states.眼部肥大细胞。正常及疾病状态下的特征。
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Culture and characterisation of epithelial cells from human pterygia.人翼状胬肉上皮细胞的培养与鉴定
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