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[Effects of low radiation doses on Chinese hamster cells].

作者信息

Shmakova N L, Fadeeva T A, Krasavin E A

机构信息

Joint Institute for Nuclear Research, Dubna, Russia.

出版信息

Radiats Biol Radioecol. 1998 Nov-Dec;38(6):841-7.

PMID:9889779
Abstract

The induction of cytogenetic damages after irradiation with single dose of gamma-rays (0.1-2 Gy) have been studied. It is shown non-linear curve for the induction of chromosome aberrations, detected by anaphase method. After irradiation in S-stage of the cell cycle at dose below 0.2 Gy the cells were more radiosensitive than after irradiation with doses 0.3-2 Gy. Between the phases of high radiosensitivity and radioresistance the reversal dose-effect relation was observed. This phenomenon was not marked for the cells after irradiation in G2-stage of the cell cycle. It is possible, this results could reflect an induced radioresistance at low dose of irradiation.

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