Mathews J E, George S, Mathews P, Mathai E, Brahmadathan K N, Seshadri L
Department of Obstetrics and Gynaecology, Christian Medical College and Hospital, Vellore, Tamilnadu, India.
Aust N Z J Obstet Gynaecol. 1998 Nov;38(4):407-10. doi: 10.1111/j.1479-828x.1998.tb03098.x.
This study was designed to compare urine microscopy and the Griess test as screening tests for asymptomatic bacteriuria (AB) in pregnancy, using urine culture as a gold standard. Urine microscopy, Griess test and urine culture were carried out on urine samples from 483 antenatal women. AB was detected by urine culture in 30 (6.8%) of the patients. The Griess test and urine microscopy were found to have a sensitivity of 63.3% and 60%, specificity of 99.5% and 83.6%; and positive predictive value of 90.5% and 21.1% respectively. Most of the infections missed by the Griess test were either <100,000 colony count on culture or caused by gram positive cocci. The cost of the Griess test was only one tenth of that of urine microscopy. The Griess test is a simple and inexpensive test that when compared to urine microscopy has equal sensitivity, and better specificity and positive predictive value for the detection of AB in pregnancy than urine microscopy.
本研究旨在以尿培养作为金标准，比较尿显微镜检查和格里斯试验作为孕期无症状菌尿（AB）筛查试验的效果。对483例产前女性的尿液样本进行了尿显微镜检查、格里斯试验和尿培养。通过尿培养在30例（6.8%）患者中检测到AB。发现格里斯试验和尿显微镜检查的敏感性分别为63.3%和60%，特异性分别为99.5%和83.6%，阳性预测值分别为90.5%和21.1%。格里斯试验漏诊的大多数感染要么培养时菌落计数<100,000，要么由革兰氏阳性球菌引起。格里斯试验的成本仅为尿显微镜检查的十分之一。格里斯试验是一种简单且廉价的试验，与尿显微镜检查相比，在检测孕期AB方面具有相同的敏感性、更好的特异性和阳性预测值。
