Wadd N J, Lucraft H H
Northern Centre for Cancer Treatment, Newcastle General Hospital, Newcastle upon Tyne, UK.
Clin Oncol (R Coll Radiol). 1998;10(6):399-400. doi: 10.1016/s0936-6555(98)80040-x.
We report two cases of presumed radiation-induced brachial plexus neuropathy in patients with lymphoma who were treated with standard mantle radiotherapy to a dose of 40 Gy in 20 fractions. Radiation-induced brachial plexopathy has not previously been reported following mantle irradiation at this dose. Both patients received chemotherapy in relapse. We postulate three possible causes: enhanced radiation sensitivity; an interaction between the chemotherapy and the radiotherapy; or an increased dose in axilla owing to a smaller separation at that point.
我们报告了两例淋巴瘤患者疑似放射性臂丛神经病变的病例，这些患者接受了标准的斗篷式放射治疗，剂量为40 Gy，分20次进行。此前尚未有关于在此剂量斗篷式照射后发生放射性臂丛神经病变的报道。两名患者在复发时均接受了化疗。我们推测了三种可能的原因：放射敏感性增强；化疗与放疗之间的相互作用；或由于该部位间距较小导致腋窝剂量增加。
