McCluggage W G, Nirmala V, Radhakumari K
Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland.
Int J Gynecol Pathol. 1999 Jan;18(1):94-5. doi: 10.1097/00004347-199901000-00016.
A 24-year-old pregnant woman was found to have a mass in the posterior vagina; a partly cystic and partly solid lesion was excised. Histology showed a papillary mural neoplasm covered by intact squamous epithelium. Immunohistochemical staining showed diffuse positivity with CAM 5.2, EP4, CEA, and EMA and focal immunoreactivity with CA-125. This lesion was interpreted as an intramural mullerian papilloma, only the second such tumor described in the vagina and the first in an adult.
一名24岁孕妇被发现阴道后壁有一肿物；切除了一个部分囊性、部分实性的病变。组织学检查显示为一个被完整鳞状上皮覆盖的乳头状壁内肿瘤。免疫组化染色显示CAM 5.2、EP4、癌胚抗原（CEA）和上皮膜抗原（EMA）弥漫阳性，以及CA-125局灶性免疫反应。该病变被解释为壁内苗勒管乳头状瘤，是阴道内描述的第二例此类肿瘤，也是成人中的首例。
