[去皮质素（16-亚甲基泼尼松龙）对胎儿肺卵磷脂合成影响的体内及体外研究（作者译）]
[In vivo and in vitro investigations of the effect of decortilen (16-methylenprednisolone) on lecithin synthesis in the fetal lung (author's transl)].
作者信息
Gerner R, Halberstadt E, Fortmeyer H P
出版信息
Z Geburtshilfe Perinatol. 1976 Jun;180(3):183-8.
PMID:989208
Abstract
Lecithin synthesis in fetal lungs of the rat over three-fold methylation and over choline and CDP-choline was quantitatively determined via the incorporation rate of marked metabolites. The ability of decortilen to influence both modes of synthesis was investigated. In vivo and in vitro, the glucocorticoid stimulates lecithin formation, which can be as high as 200%, only over choline and CDP-choline.
摘要
通过标记代谢物的掺入率，定量测定了大鼠胎儿肺中卵磷脂在三倍甲基化以及胆碱和CDP - 胆碱上的合成情况。研究了去皮质酮影响这两种合成模式的能力。在体内和体外，糖皮质激素仅通过胆碱和CDP - 胆碱刺激卵磷脂的形成，刺激率可高达200%。
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