关于通过糖皮质激素对胎儿肺卵磷脂合成进行最佳刺激的实验研究（作者译）
[Experimental investigations in regard to the optimal stimulation of lecithin synthesis in the fetal lung via glucocorticoids (author's transl)].
作者信息
Gerner R, Halberstadt E
出版信息
Z Geburtshilfe Perinatol. 1976 Jun;180(3):189-93.
PMID:989209
Abstract
On the basis of curves illustrating the effects of dosage on experimental animals, it was shown that glucocorticoids inhibit as well as stimulate lecithin synthesis in the fetal lung. Equivalent doses of corticoids produce comparable results. It was established that the concentration necessary to produce an optimal stimulation of lecithin synthesis was 0.5 to 2.0 mg/kg body weight.
摘要
根据说明剂量对实验动物影响的曲线表明，糖皮质激素既能抑制也能刺激胎儿肺中卵磷脂的合成。同等剂量的皮质激素产生类似的结果。已确定产生卵磷脂合成最佳刺激所需的浓度为0.5至2.0毫克/千克体重。
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