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羊水表面活性剂:生物力学与生化分析的比较(作者译)

[Surfactants in amniotic fluids: a comparision between biomechanical and biochemical analyses (author's transl)].

作者信息

Krieglsteiner H P, Köpcke H, Lohninger A, Schneider R, Landauer B, Johannigmann J, Blümel G

出版信息

Z Geburtshilfe Perinatol. 1976 Jun;180(3):194-203.

PMID:989210
Abstract

44 specimens of amniotic fluid from the 25 week's gestation onwards were tested in a modified Wilhelmy-Langmuir surface balance. In addition percentage of lecithin in total phospholipids, total phospholipd phosphorus concentration and fatty acid composition of lecithin was determined. Lecithin, total phospholipid-phosphorus and palmitic acid show significant rises in concentration with gestational progress. The results of the surface tension measurements are significantly correlated with the biochemical analysis. Therefore, fetal lung maturity seems to be well estimated by the biomechanical method.

摘要

从妊娠25周起,对44份羊水样本在改良的Wilhelmy-Langmuir表面天平上进行检测。此外,还测定了总磷脂中卵磷脂的百分比、总磷脂磷浓度以及卵磷脂的脂肪酸组成。卵磷脂、总磷脂磷和棕榈酸的浓度随孕周增加而显著升高。表面张力测量结果与生化分析显著相关。因此,生物力学方法似乎能够很好地评估胎儿肺成熟度。

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