Herrera J L
Division of Gastroenterology, University of South Alabama College of Medicine, Mobile Ala. 36617,
Dig Dis. 1998 Sep-Oct;16(5):274-83. doi: 10.1159/000016877.
Acute liver failure represents one of the most challenging conditions in gastroenterology. In most cases, there is no effective therapy making supportive intensive care the most important management tool. These patients frequently develop multi-organ failure, placing them at risk of systemic infections, cerebral edema, hemodynamic instability, coagulopathy and various renal and metabolic complications. Successful management of the patient with acute liver failure requires an understanding of the pathophysiology and management of these complications. An overview of acute liver failure and its most common complications is presented.
急性肝衰竭是胃肠病学中最具挑战性的病症之一。在大多数情况下,没有有效的治疗方法,支持性重症监护成为最重要的管理手段。这些患者常出现多器官功能衰竭,使其面临全身感染、脑水肿、血流动力学不稳定、凝血病以及各种肾脏和代谢并发症的风险。成功管理急性肝衰竭患者需要了解这些并发症的病理生理学和管理方法。本文将概述急性肝衰竭及其最常见的并发症。