Nakamura K, Kashima K, Koike Y
Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan.
ORL J Otorhinolaryngol Relat Spec. 1999 Jan-Feb;61(1):10-5. doi: 10.1159/000027631.
The blink reflex excitability recovery curves were studied in 12 patients with postparalytic facial dysfunctions (PPFD) and 12 healthy control subjects. The inhibitory effects of the conditioning stimuli on the ipsilateral R2 and contralateral R2 responses observed in control subjects were significantly less in patients with PPFD. The enhanced recovery of the R2 responses was similar on the affected side and unaffected side in the patients. These results indicate that patients with PPFD have an increased excitability of central interneurons which mediate the R2 pathway. It is suggested that not only changes in the peripheral facial nerve but also changes in the central nervous system may contribute to the onset of PPFD.
对12例麻痹后面部功能障碍（PPFD）患者和12名健康对照者进行了瞬目反射兴奋性恢复曲线研究。PPFD患者中，条件刺激对对照者同侧R2和对侧R2反应的抑制作用明显减弱。患者患侧和未患侧R2反应的恢复增强情况相似。这些结果表明，PPFD患者介导R2通路的中枢中间神经元兴奋性增加。提示不仅周围面神经的改变，而且中枢神经系统的改变都可能导致PPFD的发生。
