Chandra S V, Shukla G S
Arch Toxicol. 1976 Aug 18;35(4):319-23. doi: 10.1007/BF00570272.
Daily intraperitoneal administration of manganese chloride (15 mg/kg) to rats, maintained on an irondeficient diet, produced marked alterations in the activity of succinic dehydrogenase, monoamine oxidase, and in the morphology of the liver. Manganese accumulation was also significantly increased in such rats than after similar treatment to normally fed rats. Iron deficiency leads to increased absorption of manganese which is responsible for increased susceptibility to manganese toxicity in these animals.
给维持缺铁饮食的大鼠每日腹腔注射氯化锰（15毫克/千克），会使琥珀酸脱氢酶、单胺氧化酶的活性以及肝脏形态发生显著改变。与正常喂养的大鼠接受类似处理后相比，此类大鼠体内的锰蓄积量也显著增加。缺铁会导致锰吸收增加，这是这些动物对锰毒性易感性增加的原因。
