Ford H L, Pardee A B
Dana-Farber Cancer Institute, Boston, Massachusetts 02115-6084, USA.
J Cell Biochem Suppl. 1998;30-31:1-7.
Events in the S phase of the cell cycle have been investigated to a relatively limited extent in comparison with those in G1 and M phases. Four aspects of S are briefly discussed in this report: (1) the final biochemical step permitting initiation of DNA synthesis, (2) determination of replication timing of individual genes and its mechanism, (3) S phase processes that lead to the onset of M phase, and (4) resetting the S-phase machinery.
与细胞周期G1期和M期的事件相比，人们对S期事件的研究程度相对有限。本报告简要讨论了S期的四个方面：（1）允许启动DNA合成的最终生化步骤；（2）单个基因复制时间的确定及其机制；（3）导致M期开始的S期过程；（4）重置S期机制。
