Scheer M
Arzneimittelforschung. 1976;26(5):778-81.
10 mg/kg of strepto-, neo-, kanamycin, genta- and sisomicin were applied s.c. to rats in lactation. After 0.5, 1, 2, 4, 6, 8 and 24 h the animals were milked. The antibacterial concentrations in the milk were determined in comparison to the serum concentrations. Strepto-, neo- and kanamycin showed the highest concentrations in the serum, genta- and sisomicin the highest in the milk.
将链霉素、新霉素、卡那霉素、庆大霉素和西索米星以10毫克/千克的剂量皮下注射给哺乳期大鼠。在0.5、1、2、4、6、8和24小时后采集动物乳汁。测定乳汁中的抗菌浓度并与血清浓度进行比较。链霉素、新霉素和卡那霉素在血清中的浓度最高,庆大霉素和西索米星在乳汁中的浓度最高。