抗血脂药。第3部分：14C放射性标记的异丙基-[（4'-氯苯甲酰基）-2-苯氧基-2-甲基] -丙酸酯（LF-178）的合成
Antilipidemic drugs. Part 3: On the synthesis of 14C-radiolabelled isopropyl-[4'-chlorobenzoyl)-2-phenoxy-2-methyl]-propionate (LF-178).
作者信息
Duc C L
出版信息
Arzneimittelforschung. 1976;26(5):894-5.
PMID:989364
Abstract
Isopropyl-[4'-(p-chlorobenzoyl)-2-phenoxy-2 methyl]-propionate (LF 178; procetofene; Lipanthyl¿) was labelled with 14C. The carbon atom of the ketone function was chosen for the study. The obtained product has a total specific radioactivity of 8.79 mCi/mM. Its structure was proved by NMR.
摘要
异丙基-[4'-(对氯苯甲酰基)-2-苯氧基-2-甲基]-丙酸酯（LF 178；普罗布考；利平多¿）用¹⁴C进行标记。选择酮官能团的碳原子进行研究。得到的产物总比活度为8.79毫居里/毫摩尔。其结构通过核磁共振得以证实。
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