Marran L, Schor C M
Vision Science Group, University of California, Berkeley 94720, USA.
Vision Res. 1998 Nov;38(22):3601-19. doi: 10.1016/s0042-6989(98)00064-9.
Despite the evidence for consensual accommodation in response to consensual accommodative stimuli, only a few studies have investigated the binocular accommodative response to unequal (aniso) accommodative stimuli. Past studies investigating an unequal binocular accommodative response (aniso-accommodation) to aniso-accommodative stimuli have been limited by viewing conditions and measurement technique making the results, which were equivocal, difficult to interpret. This investigation addressed these limitations by the following design parameters: (1) monocular dichoptic blur cuese were provided in the binocular stimulus target to provide subjects feedback on their aniso-accommodative response and to alert the investigator of a monocular blur suppression response; (2) a training period was provided; (3) in the subjective method, each eye's stigma was positioned near the dichoptic letter viewed by the other eye. By this method, a true aniso-accommodative response could be differentiated from successive consensual responses; (4) a large range of aniso-accommodative stimuli was used, 0.50-3.0 D, presented in incremental steps of 0.5 D, allowing measurement of an average 0.75 D aniso-accommodative response for the highest (3.0 D) aniso-accommodative stimulus; (5) aniso-accommodation was measured as a function of viewing distance. For four of seven subjects, the gain of the aniso-accommodative response was significantly greater at near than at far viewing distances; (6) aniso-accommodation was confirmed objectively with measures of the response to steady state and step aniso-accommodative stimuli, using a binocular SRI Dual Purkinje Eye Tracker Optometer System. The aniso-accommodative response to step stimuli showed a very long latency period (about 11 s) and a response time of 4.5 s. A potential benefit of aniso-accommodation would be to overcome small amounts of uncorrected anisometropic refractive error. This would preserve fine stereo acuity which is impaired by unequal intraocular image contrast. Aniso-accommodation also may provide an appropriate efferent feedback signal for each eye's unique refractive error which could be used to guide developmental isometropization (attainment of equal refractive error in the two eyes.).
尽管有证据表明存在对双眼调节性刺激的双眼调节反应,但仅有少数研究探讨了对不等(异)调节性刺激的双眼调节反应。过去研究不等双眼调节反应(异向调节)对异向调节性刺激的研究受到观察条件和测量技术的限制,使得结果模棱两可,难以解释。本研究通过以下设计参数解决了这些限制:(1)在双眼刺激目标中提供单眼双视模糊线索,以向受试者提供其异向调节反应的反馈,并提醒研究者注意单眼模糊抑制反应;(2)设置了一个训练期;(3)在主观方法中,每只眼睛的视标位于另一只眼睛所观察的双视字母附近。通过这种方法,可以将真正的异向调节反应与连续的双眼反应区分开来;(4)使用了范围为0.50 - 3.0 D的大量异向调节性刺激,以0.5 D的增量步长呈现,从而能够测量最高(3.0 D)异向调节性刺激下平均0.75 D的异向调节反应;(5)异向调节作为观察距离的函数进行测量。对于七名受试者中的四名,异向调节反应的增益在近观察距离处显著大于远观察距离处;(6)使用双眼SRI双浦肯野眼追踪验光仪系统,通过对稳态和阶梯式异向调节性刺激反应的测量,客观地确认了异向调节。对阶梯式刺激的异向调节反应显示出非常长的潜伏期(约11秒)和4.5秒的反应时间。异向调节的一个潜在益处是克服少量未矫正的屈光参差性屈光不正。这将保留因双眼内图像对比度不等而受损的精细立体视锐度。异向调节还可能为每只眼睛独特的屈光不正提供适当的传出反馈信号,该信号可用于指导发育性等视度化(双眼屈光不正相等的实现)。