Wolffsohn James Stuart, Hunt Olivia Anne, Naroo Shehzad, Gilmartin Bernard, Shah Sunil, Cunliffe Ian Andrew, Benson Mark Timothy, Mantry Sanjay
School of Life and Health Sciences, Aston University, Birmingham, United Kingdom.
Invest Ophthalmol Vis Sci. 2006 Mar;47(3):1230-5. doi: 10.1167/iovs.05-0939.
To compare the objective accommodative amplitude and dynamics of eyes implanted with the one-compartment-unit (1CU; HumanOptics AG, Erlangen, Germany) accommodative intraocular lenses (IOLs) with that measured subjectively.
Twenty eyes with a 1CU accommodative IOL implanted were refracted and distance and near acuity measured with a logMAR (logarithm of the minimum angle of resolution) chart. The objective accommodative stimulus-response curve for static targets between 0.17 and 4.00 D accommodative demand was measured with the SRW-5000 (Shin-Nippon Commerce Inc., Tokyo, Japan) and PowerRefractor (PlusOptiX, Nürnberg, Germany) autorefractors. Continuous objective recording of dynamic accommodation was measured with the SRW-5000, with the subject viewing a target moving from 0 to 2.50 D at 0.3 Hz through a Badal lens system. Wavefront aberrometry measures (Zywave; Bausch & Lomb, Rochester, NY) were made through undilated pupils. Subjective amplitude of accommodation was measured with the RAF (Royal Air Force accommodation and vergence measurement) rule.
Four months after implantation best-corrected acuity was -0.01 +/- 0.16 logMAR at distance and 0.60 +/- 0.09 logMAR at near. Objectively, the static amplitude of accommodation was 0.72 +/- 0.38 D. The average dynamic amplitude of accommodation was 0.71 +/- 0.47 D, with a lag behind the target of 0.50 +/- 0.48 seconds. Aberrometry showed a decrease in power of the lens-eye combination from the center to the periphery in all subjects (on average, -0.38 +/- 0.28 D/mm). Subjective amplitude of accommodation was 2.24 +/- 0.42 D. Two years after 1CU implantation, refractive error and distance visual acuity remained relatively stable, but near visual acuity, and the subjective and objective amplitudes of accommodation decreased.
The objective accommodating effects of the 1CU lens appear to be limited, although patients are able to track a moving target. Subjective and objective accommodation was reduced at the 2-year follow-up. The greater subjective amplitude of accommodation is likely to result from the eye's depth of focus of and the aspheric nature of the IOL.
比较植入单腔单元（1CU；德国埃尔朗根市HumanOptics AG公司）可调节人工晶状体（IOL）的眼睛的客观调节幅度和动态变化与主观测量结果。
对20只植入1CU可调节IOL的眼睛进行验光，并用logMAR（最小分辨角对数）视力表测量远视力和近视力。使用SRW - 5000（日本东京新日本商事株式会社）和PowerRefractor（德国纽伦堡PlusOptiX公司）自动验光仪测量0.17至4.00 D调节需求之间静态目标的客观调节刺激 - 反应曲线。通过Badal透镜系统，让受试者观看以0.3 Hz从0移动到2.50 D的目标，使用SRW - 5000连续客观记录动态调节。通过未散瞳的瞳孔进行波前像差测量（ZyWave；美国纽约罗切斯特市博士伦公司）。使用RAF（皇家空军调节和聚散测量）规则测量主观调节幅度。
植入后4个月，最佳矫正视力在远视力为-0.01±0.16 logMAR，近视力为0.60±0.09 logMAR。客观上，静态调节幅度为0.72±0.38 D。平均动态调节幅度为0.71±0.47 D，滞后于目标0.50±0.48秒。像差测量显示所有受试者中晶状体 - 眼组合的屈光力从中心到周边均降低（平均为-0.38±0.28 D/mm）。主观调节幅度为2.24±0.42 D。植入1CU两年后，屈光不正和远视力保持相对稳定，但近视力以及主观和客观调节幅度下降。
尽管患者能够追踪移动目标，但1CU晶状体的客观调节效果似乎有限。在2年随访时主观和客观调节均降低。主观调节幅度较大可能是由于眼睛的焦深和IOL的非球面性质所致。
