Lehmann E
Arzneimittelforschung. 1976;26(6):1132-3.
This investigation was carried out to test the hypotheses that the reactions associated with external stress are better reduced by barbiturates while meprobamat-type tranquilizers reduce principally internal stress. To test the interaction of medication and type of stress a 3X3 plan was used with independent groups. The medication conditions were: placebo, 500 mg tybamate, and 100 mg secobarbital, and the stress conditions were: white noise of 95 dB intensity (external stress), fictitious assessments of the subject with high negative content (internal stress) and a non-stress situation. The paper deals with the main effects on physiological and subjective variables as the result of a covariance analysis. No interactions were found.
巴比妥类药物能更好地减轻与外部压力相关的反应，而甲丙氨酯类镇静剂主要减轻内部压力。为了测试药物与压力类型的相互作用，采用了一个3×3的独立组设计方案。药物条件为：安慰剂、500毫克甲丙氨酯和100毫克速可眠，压力条件为：95分贝强度的白噪声（外部压力）、对受试者具有高度负面内容的虚拟评估（内部压力）和非压力情境。本文通过协方差分析探讨了对生理和主观变量的主要影响。未发现相互作用。
