Kilmer D D
Department of Physical Medicine and Rehabilitation, University of California, Davis Medical Center, Sacramento, USA.
Phys Med Rehabil Clin N Am. 1998 Feb;9(1):115-25, vi.
Persons with hereditary neuromuscular diseases generally lead a sedentary lifestyle, placing them at risk for diseases associated with inactivity and causing weakness, which compounds their primary disease. Although research is lacking in this area, evidence to date suggests that this population may benefit from both strengthening and aerobic fitness training programs. Overwork weakness has not been demonstrated in controlled trials of exercise, but clinicians need to be prudent in their recommendations, encouraging alternating periods of physical activity with scheduled rest. Future investigations should focus on the primary symptom of fatigue, and quantify changes in the ability to work and participate in physical activities as outcome measures of an exercise program.
患有遗传性神经肌肉疾病的人通常生活方式久坐不动，这使他们面临与缺乏运动相关的疾病风险，并导致身体虚弱，而这又会加重他们的原发性疾病。尽管该领域缺乏研究，但迄今为止的证据表明，这一人群可能从强化训练和有氧健身训练计划中受益。在运动的对照试验中尚未证实过度劳累导致的虚弱，但临床医生在给出建议时应谨慎，鼓励在进行体育活动的时间段与安排好的休息时间之间交替。未来的研究应关注疲劳这一主要症状，并量化工作能力和参与体育活动能力的变化，以此作为运动计划的结果指标。
