Ng P P, Ng S K, Chng H H
National Skin Centre, Singapore.
Clin Exp Dermatol. 1998 Jul;23(4):181-4. doi: 10.1046/j.1365-2230.1998.00367.x.
A 49-year-old woman with systemic lupus erythematosus, and a history of thymoma and chronic white plaques of the oral mucosa, developed a blistering eruption which was diagnosed as pemphigus foliaceus based on clinical, histological and direct immunofluorescence findings. However, the white plaques had both the clinical and histological features of lichen planus, as well as intercellular antibodies suggestive of pemphigus. Such conditions in combination have been documented previously, but this is believed to be the first report of the coexistence of all four in one individual. The common mechanism underlying these four conditions may well be an immunological disturbance.
一名49岁患有系统性红斑狼疮、有胸腺瘤病史且口腔黏膜有慢性白色斑块的女性，出现了水疱性皮疹，根据临床、组织学和直接免疫荧光检查结果诊断为落叶型天疱疮。然而，白色斑块具有扁平苔藓的临床和组织学特征，以及提示天疱疮的细胞间抗体。此前已有这些情况合并出现的记录，但据信这是首例这四种情况在同一个体中共存的报告。这四种情况共同的潜在机制很可能是免疫紊乱。
