Helm T N, Camisa C, Liu A Y, Valenzuela R, Bergfeld W F
Department of Dermatology, Cleveland Clinic Foundation, OH 44195-5032.
J Am Acad Dermatol. 1994 Feb;30(2 Pt 1):219-24. doi: 10.1016/s0190-9622(94)70020-6.
Individual case reports have suggested an occasional association of lichen planus with internal malignancy.
Our purpose was to describe five patients with a neoplastic disease in whom lichen planus developed.
Serologic and immunopathologic studies were conducted.
No evidence of autoantibody production characteristic of paraneoplastic pemphigus was found, and antibodies reactive with basal cell keratinocytes were not detected.
Lichen planus may be rarely induced by neoplasia. A cell-mediated immune reaction possibly causes this phenomenon.
个别病例报告提示扁平苔藓与内部恶性肿瘤偶尔存在关联。
我们的目的是描述五例发生扁平苔藓的肿瘤性疾病患者。
进行了血清学和免疫病理学研究。
未发现副肿瘤性天疱疮特征性自身抗体产生的证据，也未检测到与基底细胞角质形成细胞反应的抗体。
肿瘤可能很少诱发扁平苔藓。细胞介导的免疫反应可能导致这种现象。
