Skamel H J, Hanusch A, Mathias K
Radiologische Klinik, Städtische Kliniken Dortmund.
Aktuelle Radiol. 1998 Nov;8(6):273-7.
Comparison between fine needle aspiration (FNAB) and automated coaxial core biopsy (ACCB) of CT-guided thoracal and abdominal biopsies.
98 patients had CT-guided biopsies of the liver (n = 26), lung (n = 36), pancreas (n = 8), presacral space (n = 16), retroperitoneum (n = 8), groin (n = 1) and mediastinum (n = 3). In 50 patients fine needle aspiration, in 48 patients ACCB was performed. Nine physicians, two of them with advanced experience, performed the procedure.
Histologically satisfying material was achieved in 76% of the biopsies with FNAB, in 100% with ACCB. The sensitivity within the FNAB group was 59.6%, within ACCB group 97.5%. Sensitivity for the whole group was 76.7%. In pulmonary lesions the sensitivity was increased to 100% by using the ACCB method in comparison to FNAB (58%), in liver lesions from 75% (FNAB) to 92% (ACCB). 19 of 20 false negative specimens were obtained with FNAB. The less experienced physicians had a false negative rate of 43% with FNA biopsies, but only 2.2% with ACCB.
In pulmonary and abdominal lesions ACCB is a procedure with rare complications and low invasivity, which is not dependent on the performing person. ACCB has a high diagnostic accuracy and should replace FNAB.
比较CT引导下胸腹部活检的细针穿刺抽吸活检(FNAB)与自动同轴芯针活检(ACCB)。
98例患者接受了CT引导下的肝脏活检(n = 26)、肺部活检(n = 36)、胰腺活检(n = 8)、骶前间隙活检(n = 16)、腹膜后活检(n = 8)、腹股沟活检(n = 1)和纵隔活检(n = 3)。其中50例患者接受细针穿刺抽吸活检,48例患者接受自动同轴芯针活检。由9名医生进行操作,其中2名经验丰富。
FNAB活检中76%获得了组织学满意的标本,ACCB活检则为100%。FNAB组的敏感性为59.6%,ACCB组为97.5%。整个组的敏感性为76.7%。在肺部病变中,与FNAB(58%)相比,ACCB方法的敏感性提高到了100%;在肝脏病变中,从FNAB的(75%)提高到了ACCB的92%。20份假阴性标本中有19份是通过FNAB获得的。经验较少的医生进行FNA活检时假阴性率为43%,而ACCB活检时仅为2.2%。
对于肺部和腹部病变,ACCB是一种并发症少、侵入性低且不依赖操作者的检查方法。ACCB具有较高的诊断准确性,应取代FNAB。