Georgiev O P, Lal S M, Gupta N, Ross G
Department of Internal Medicine, University of Missouri Health Sciences Center Columbia, 65212, USA.
Int J Artif Organs. 1998 Nov;21(11):702-4.
We describe a renal transplant patient who developed hypercalcemia during treatment with ganciclovir for cytomegaloviral (CMV) infection. To our knowledge such an association has not previously been reported. Hypercalcemia was associated with low levels of serum parathormone (PTH) and an increase in 1,25 dihydroxy vitamin D concentrations. The mechanism(s) of ganciclovir-associated hypercalcemia remains unclear.
我们描述了一名肾移植患者，该患者在接受更昔洛韦治疗巨细胞病毒（CMV）感染期间出现了高钙血症。据我们所知，这种关联以前尚未有过报道。高钙血症与血清甲状旁腺激素（PTH）水平降低以及1,25-二羟维生素D浓度升高有关。更昔洛韦相关性高钙血症的机制仍不清楚。
