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准分子激光角膜切削术后复发性角膜上皮下混浊

Recurrent subepithelial corneal opacities after excimer laser phototherapeutic keratectomy.

作者信息

Starr M B

机构信息

Manhattan Eye, Ear, and Throat Hospital, Mount Sinai School of Medicine, New York, New York, USA.

出版信息

Cornea. 1999 Jan;18(1):117-20.

PMID:9894948
Abstract

PURPOSE

To report the recurrence of presumed post-viral conjunctivitis subepithelial corneal opacities after excimer laser phototherapeutic keratectomy (PTK).

METHOD

Case report.

RESULTS

A 33-year-old ophthalmic technician developed recurrence of opacities after treatment of presumed post-viral keratitis subepithelial corneal opacities with the excimer laser.

CONCLUSIONS

Post-viral keratitis subepithelial corneal opacities may recur after removal by excimer laser PTK. Recurrence of these opacities in anterior corneal stroma previously unaffected by opacities before laser treatment suggests the presence of viral antigen in deeper corneal tissue than that occupied by the original subepithelial opacities. The recurrence also suggests likely routes of corneal antibody penetration in the formation of these opacities. Intensive topical steroid treatment may play a role by increasing the depth of viral particle penetration into corneal stroma.

摘要

目的

报告准分子激光角膜切削术(PTK)后假定的病毒性结膜炎所致角膜上皮下混浊复发情况。

方法

病例报告。

结果

一名33岁眼科技术员在准分子激光治疗假定的病毒性角膜炎所致角膜上皮下混浊后,混浊复发。

结论

准分子激光PTK去除病毒性角膜炎所致角膜上皮下混浊后可能复发。这些混浊在激光治疗前未受混浊影响的角膜前基质中复发,提示病毒抗原存在于比原始上皮下混浊所占据的更深的角膜组织中。复发还提示了这些混浊形成过程中角膜抗体渗透的可能途径。强化局部类固醇治疗可能通过增加病毒颗粒渗透到角膜基质的深度而发挥作用。

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