Conces D J
Department of Radiology, Indiana University School of Medicine, Indianapolis, USA.
J Thorac Imaging. 1999 Jan;14(1):1-8. doi: 10.1097/00005382-199901000-00001.
The endemic fungi Histoplasma capsulatum, Coccidioides immitis, and Blastomyces dermatitidis tend to reside in specific geographic regions. The organisms are pathogenic in that they are able to produce clinical disease in both immunocompromised patients and in patients with normal immunity. These organisms have a variety of clinical presentations, some of which typically are seen in the normal host and others that are primarily encountered in persons with abnormal immunity. Although most of the cases are seen in endemic regions, they may occur in persons who at some time either resided in or traveled to an endemic region.
地方性真菌荚膜组织胞浆菌、粗球孢子菌和皮炎芽生菌往往存在于特定的地理区域。这些微生物具有致病性，因为它们能够在免疫功能低下的患者和免疫功能正常的患者中引发临床疾病。这些微生物有多种临床表现，其中一些通常见于正常宿主，而另一些则主要见于免疫功能异常的人群。虽然大多数病例见于地方性流行区域，但也可能发生在曾在地方性流行区域居住或旅行过的人身上。
