Tharakan J, Hossenbocus A, Arthur M J
Department of Medicine and Gastroenterology, St Mary's Hospital, Newport, Isle of Wight.
Eur J Gastroenterol Hepatol. 1998 Dec;10(12):1055-6. doi: 10.1097/00042737-199812000-00013.
Macroenzymes are serum enzymes that have a greater molecular mass than the corresponding enzyme normally found in serum (Klonoff. West J Med 1980; 133: 392-407). Serum AST (aspartate aminotransferase) has rarely been reported to complex with immunoglobulins, resulting in an elevation in serum AST activity. Physicians should be aware of this condition so that patients are not subjected to invasive and costly procedures unnecessarily (Litin et al. Mayo Clin Proc 1987; 62: 681-687). We report on such a patient with a raised AST due to macroenzyme formation.
巨酶是指分子量比血清中正常存在的相应酶更大的血清酶（克洛诺夫。《西医学杂志》1980年；133: 392 - 407）。血清天冬氨酸氨基转移酶（AST）很少被报道与免疫球蛋白结合，导致血清AST活性升高。医生应了解这种情况，以免患者不必要地接受侵入性和昂贵的检查（利廷等人。《梅奥诊所学报》1987年；62: 681 - 687）。我们报告了一名因形成巨酶而导致AST升高的患者。
