Wang J, Yu J, Pan S, Ni B
Department of Psychiatry, Qingdao Medical College Qingdao Mental Hospital, China.
Psychiatry Clin Neurosci. 1998 Dec;52 Suppl:S295-6. doi: 10.1111/j.1440-1819.1998.tb03249.x.
According to the popular spot check method we investigated 14,684 partial community persons. The screen instrument used was the MMSE. Positive cases were through ADL, HDS and detailed psychical examination by two doctors according to the CCMD-2 to establish a definite diagnosis. Differential diagnosis between AD and MID was carried out according to HIS result. A total of 1448 persons were over 60 years, which amounted to 9.98% of the entire population. Of a total of 672 men and 776 females, 13 suffered senile dementia, which made up 0.995% of the aged. There were seven MID (5 males, 2 females) and six AD (2 males, 4 females). Family histories showed that one AD had the same symptoms as her twin sister. Two AD and four MD drank Chinese spirit 2-4 liang per day for 20 years, 80% of patients were nursed by the son or daughter-in-law, but they believed wrongly that 'It is necessary to cure the old'. Six of 13 had a long period of drinking history, four of six for MID. This has shown that dementia partly relates to drink especially for MID. Early case can be detected through daily life activities such as buying food, playing cards etc. Activities of daily living may avoid the pseudo-positive which is caused by educational level.
按照普遍采用的抽样调查方法,我们对14684名部分社区居民进行了调查。所使用的筛查工具为简易精神状态检查表(MMSE)。阳性病例通过日常生活能力量表(ADL)、长谷川痴呆量表(HDS)以及由两名医生根据中国精神疾病分类方案与诊断标准第二版(CCMD - 2)进行详细的精神检查来确诊。根据HIS结果进行阿尔茨海默病(AD)与多发梗死性痴呆(MID)的鉴别诊断。共有1448人年龄超过60岁,占总人数的9.98%。在这672名男性和776名女性中,有13人患有老年痴呆症,占老年人的0.995%。其中有7例MID(5例男性,2例女性)和6例AD(2例男性,4例女性)。家族史显示,1例AD患者与其双胞胎姐妹症状相同。2例AD患者和4例MID患者每天饮用2至4两白酒,持续20年,80%的患者由儿子或儿媳照料,但他们错误地认为“老人病需要治”。13例患者中有6例有长期饮酒史,MID患者中的6例中有4例。这表明痴呆症部分与饮酒有关,尤其是MID。通过诸如购物、打牌等日常生活活动可以早期发现病例。日常生活活动可以避免因教育程度导致的假阳性。