Osterman P O
Br J Dermatol. 1976 Nov;95(5):555-8. doi: 10.1111/j.1365-2133.1976.tb00869.x.
In three women with multiple sclerosis, paroxysmal attacks of itching occurred. There were several similarities between these attacks and other types of paroxysmal phenomena previously described in multiple sclerosis. The attacks were brief, but usually lasted several minutes, they started and ended abruptly, and recurred several times a day. The were controlled effectively by carbamazepine. It is suggested that paroxysmal itching is caused by transversely spreading ephaptic activation of axons within a partially demyelinated lesion in pain-conducting fibre tracts in the central nervous system.
在三名患有多发性硬化症的女性中，出现了阵发性瘙痒发作。这些发作与先前在多发性硬化症中描述的其他类型的阵发性现象有几个相似之处。发作短暂，但通常持续几分钟，发作开始和结束都很突然，并且每天发作几次。它们通过卡马西平得到有效控制。有人认为，阵发性瘙痒是由中枢神经系统疼痛传导纤维束中部分脱髓鞘病变内轴突的横向扩散性触突激活引起的。
