Kamysheva A S
Biull Eksp Biol Med. 1976 Sep;82(9):1066-8.
The changes in the rate and the character of energy processes in the mitochondria of the visual system of the brain caused by prolonged dark-rearing of the animals (for 2 1/2 months from the time of birth) proved to be reversible. The extent of normalization differed in the case of mitochondria of the optic cortex and the superior colliculus. After the animals were placed under normal light conditions the rate of the mentioned processes (when glutamic acid was used as a substrate) increased in the course of a two-week restorative period, and reached the control level or even exceeded it. The rate of the electron transport in the area of cytochrome c -- cytochromoxidase succinic toxidase oxidation chain decreased at the period of restoration and approached the control level. The role of specific impulsation in the age formation of the energy processes of the brain mitochondria is discussed.
由动物出生后长期饲养在黑暗环境中(长达2个半月)所引起的脑视觉系统线粒体中能量过程的速率和特性变化被证明是可逆的。视皮层和上丘线粒体的正常化程度有所不同。在将动物置于正常光照条件下后,在为期两周的恢复期间,上述过程(以谷氨酸作为底物时)的速率增加,并达到或甚至超过对照水平。在恢复期间,细胞色素c - 细胞色素氧化酶琥珀酸氧化酶氧化链区域的电子传输速率下降并接近对照水平。文中讨论了特定脉冲在脑线粒体能量过程年龄形成中的作用。